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1. Amygaz+(OP)[view] [source] 2020-03-17 01:21:28
It should help alleviating the symptoms, but is in no way a antiviral.

There's a phase 3 trial for treating pneumonia associated with coronavirus. This is based on prior work showing anti-inflammatory response in rheumatoid arthritis (https://www.ncbi.nlm.nih.gov/pubmed/8278823).

Note that the trial is happening in China (https://clinicaltrials.gov/ct2/show/NCT04261517), where the barriers of entry and approval are quite low.

replies(1): >>mirimi+Yp
2. mirimi+Yp[view] [source] 2020-03-17 05:43:12
>>Amygaz+(OP)
> After randomization, subjects take hydroxychloroquine 400mg per day for 5 days, also take conventional treatments.

Huh. I'm on 200mg/day for rheumatoid arthritis.

I wonder if I ought to double dose for a while.

replies(1): >>Amygaz+oW1
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3. Amygaz+oW1[view] [source] [discussion] 2020-03-17 17:58:21
>>mirimi+Yp
Sorry for the late reply: I don't see how it would prevent infection. It could be useful post-infection, to prevent complications and inflammation. Compared that with the standard of care right now which is simply observing the patient during their recovering.

There are a fair amount of studies who took the initial in vitro results (i.e. cell culture) suggesting non-specific antiviral activity (at that level coca-cola is also an antiviral, antimicrobial, and antitumoral, by the way), into animal or human, and they just did not pan out, because it isn't an antiviral.

replies(1): >>mirimi+Nu2
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4. mirimi+Nu2[view] [source] [discussion] 2020-03-17 20:34:37
>>Amygaz+oW1
Thank you.

I'll ask my rheumatologist about increasing the dose. In case I get infected, have trouble breathing, and can't get hospital care.

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