zlacker

>>psim1+(OP)
If this were a Bond movie, Bezos would be cackling in his secret lair about how his viral plan was coming to fruition. Bond (played by Idris Elba) would then cough on Bezos, who would whip out his antidote, which Bond would grab, escape, and release to the world before being killed by Thanos. (Pitch Meeting, call me)

>>hirund+3r
Fantasy-land aside, Bezos is the CEO of the organization that runs the GovCloud AWS region, which is almost certainly designated critical military infrastructure, JEDI-loss aside.

I would be astounded if there are many billionaires in the USA who are not this moment already taking chloroquine/hydroxychloroquine in the recommended prophylaxis doses, even outside of those deemed mission-critical by the most powerful organization on the continent.

>>sneak+Vz
I’m a bit confused why would an anti-parasite drug be used now for covid-19

>>rblatz+GJ
It should help alleviating the symptoms, but is in no way a antiviral.

There's a phase 3 trial for treating pneumonia associated with coronavirus. This is based on prior work showing anti-inflammatory response in rheumatoid arthritis (https://www.ncbi.nlm.nih.gov/pubmed/8278823).

Note that the trial is happening in China (https://clinicaltrials.gov/ct2/show/NCT04261517), where the barriers of entry and approval are quite low.

>>Amygaz+xQ
> After randomization, subjects take hydroxychloroquine 400mg per day for 5 days, also take conventional treatments.

Huh. I'm on 200mg/day for rheumatoid arthritis.

I wonder if I ought to double dose for a while.

>>mirimi+vg1
Sorry for the late reply: I don't see how it would prevent infection. It could be useful post-infection, to prevent complications and inflammation. Compared that with the standard of care right now which is simply observing the patient during their recovering.

There are a fair amount of studies who took the initial in vitro results (i.e. cell culture) suggesting non-specific antiviral activity (at that level coca-cola is also an antiviral, antimicrobial, and antitumoral, by the way), into animal or human, and they just did not pan out, because it isn't an antiviral.