zlacker

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1. mmooss+(OP)[view] [source] 2026-01-13 22:29:49
Always a fair request. I don't know it well enough or have time at the moment, but afaik it's the medical consensus:

Obesity is a disease, (mostly) not a result of behavior. Eating less and/or more activity doesn't cure people; iirc bodies adjust to retain the same amount of fat, etc. under the new conditions.

replies(3): >>sfn42+9m >>indeci+621 >>onefoo+JA1
2. sfn42+9m[view] [source] 2026-01-14 00:24:19
>>mmooss+(OP)
I don't know where you get your science man but I'm about 100% sure what you just said is completely false. Not even remotely controversial just flat out wrong.
replies(1): >>mmooss+KT
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3. mmooss+KT[view] [source] [discussion] 2026-01-14 05:36:47
>>sfn42+9m
What I said is commonplace if you look around.
replies(1): >>sfn42+gZ
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4. sfn42+gZ[view] [source] [discussion] 2026-01-14 06:40:19
>>mmooss+KT
Yeah, beliefs commonly held by people who would rather make excuses than improve their lives.
replies(1): >>mmooss+wY3
5. indeci+621[view] [source] 2026-01-14 07:10:06
>>mmooss+(OP)
Then how does ozempic, whose primary mechanism of action is to decrease appetite, work for obese people?

Yes, your body will compensate somewhat for caloric deficit, and yes, when you gain enough fat mass your adipocytes will divide, creating more/stronger hunger signals that encourage weight gain moreso than someone who was never obese.

But your body is not magic. If you feed it a sufficiently low amount of calories, it has to break down energy stores, e.g. fat, to make up the difference in energy requirements.

replies(1): >>mmooss+pY3
6. onefoo+JA1[view] [source] 2026-01-14 12:44:01
>>mmooss+(OP)
It is a disease as in “your metabolism is slow” so you need to cut food even more. It is a disease as “you have problem with controlling your impulses and therefore crave food”

Psychological diseases are not better or worse from psychical/metabolic ones. They are real, and for some of them we have or we develop medicine.

Nobody is claiming that obesity can’t be a result of a disease, but under the hood it always ends up as: calories surplus is stored as fat.

replies(1): >>sfn42+SE1
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7. sfn42+SE1[view] [source] [discussion] 2026-01-14 13:11:23
>>onefoo+JA1
Slow metabolism is a bit of a myth. By that I mean that it's not strictly wrong to say someone has a slow metabolism, but metabolism is an expression of your activity level so what you're really saying is the person is sedentary. If the person starts being more active their metabolism will necessarily increase.

So, slow metabolism is not a disease, it's not a genetic disorder, it is simply a result of the fact that someone is spending too much time on the couch.

I think this gets lost a lot when people talk about "slow metabolism", they turn it into this thing they're just helpless to influence, like they're just cursed with a slow metabolism and that's that. It's not like that at all, which is why I don't like the term. It just hides the reality of the situation.

replies(1): >>mmooss+EX3
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8. mmooss+EX3[view] [source] [discussion] 2026-01-14 22:14:58
>>sfn42+SE1
What is all that based on?
replies(1): >>sfn42+n85
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9. mmooss+pY3[view] [source] [discussion] 2026-01-14 22:17:57
>>indeci+621
> Then how does ozempic, whose primary mechanism of action is to decrease appetite, work for obese people?

That is a very interesting question.

> your body is not magic.

But it is a complex, highly adaptable system. The simplistic formula of calorie input = output is highly misleading.

> If you feed it a sufficiently low amount of calories

Sure, if you starve yourself, you'll start transitioning to dust pretty soon.

replies(1): >>indeci+CZ3
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10. mmooss+wY3[view] [source] [discussion] 2026-01-14 22:18:31
>>sfn42+gZ
It's just baseless nonsense. Doctors and researchers say otherwise.
replies(1): >>sfn42+485
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11. indeci+CZ3[view] [source] [discussion] 2026-01-14 22:23:08
>>mmooss+pY3
Somewhere between obese and dust you'll eventually hit a healthy weight.

https://pmc.ncbi.nlm.nih.gov/articles/PMC2495396/

replies(1): >>mmooss+pW8
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12. sfn42+485[view] [source] [discussion] 2026-01-15 06:52:27
>>mmooss+wY3
And you still haven't found the time to show me any of them.
replies(1): >>mmooss+wW8
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13. sfn42+n85[view] [source] [discussion] 2026-01-15 06:55:04
>>mmooss+EX3
Knowledge and understanding.
replies(1): >>mmooss+tW8
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14. mmooss+pW8[view] [source] [discussion] 2026-01-16 06:33:24
>>indeci+CZ3
That's a report on one person under direct medical supervision. The general consensus, afaik, is that starving yourself doesn't work, at least not more than short term - the weight comes right back.
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15. mmooss+tW8[view] [source] [discussion] 2026-01-16 06:33:59
>>sfn42+n85
So nothing.
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16. mmooss+wW8[view] [source] [discussion] 2026-01-16 06:34:21
>>sfn42+485
Show us a basis for what you say.
replies(1): >>sfn42+vp9
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17. sfn42+vp9[view] [source] [discussion] 2026-01-16 11:38:16
>>mmooss+wW8
I asked first. You're the one claiming all this scientific and expert consensus. I'm just talking common sense stuff that pretty much everyone agree on. This is simply the basics of how the body works. I could take some time to find some sources but so could you and you aren't so why should I?

It's pretty clear that you're thoroughly convinced of your own bullshit anyway, if you had any interest at all in finding the truth you'd do some light googling and find that pretty much everything I'm saying is true. I'm not interested in wasting my time finding arbitrary sources for common knowledge that you're just going to ignore anyway.

You don't have to find sources for me, I know they don't exist and if you find anything it's going to be obvious bullshit anyway. There are no serious doctors, nutritionists nor researchers who have any doubt whatsoever regarding what the roles and relationships of food and fat are in the human body. You're obviously just delusional. So good luck with that, I hope you can get past your issues and improve your life some day.

replies(1): >>accide+8H9
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18. accide+8H9[view] [source] [discussion] 2026-01-16 14:15:22
>>sfn42+vp9
You admitted to me a few days ago that you are so fat that it makes you miserable. If direct, personal experience with it not working doesn't convince you, nothing will.
replies(1): >>sfn42+8Q9
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19. sfn42+8Q9[view] [source] [discussion] 2026-01-16 15:06:56
>>accide+8H9
Are you juggling two accounts?

Yeah I said I find it miserable to be moderately overweight. I never said being more active and eating less doesn't work. It works great when I do it. I was under 90kg last year after just a few months of being active and eating better. And when I stop being active and start eating too much food, I gain weight. Which is literally exactly what I'm saying. So, I have direct personal experience with my advice working exactly the way I'm telling you it does.

At this point I'm just saying the same shit I said in the other comment already. The fact that I find it hard to follow my own advice, which I just told you because I thought it might help get my point across, is completely irrelevant to whether the advice works.

Anyway I'm over this whole conversation at this point. Do and believe whatever you want. I've said what I wanted to say. If you don't believe me that's fine, I don't care.

replies(1): >>accide+9md
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20. accide+9md[view] [source] [discussion] 2026-01-17 18:35:59
>>sfn42+8Q9
Methylmercury cysteine is an extra amino acid, and obesity is indistinguishable from mild kwashiorkor.

You are simply wrong about how everything involved works. It's a diseased, swollen tissue, not "energy storage".

replies(1): >>sfn42+sHd
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21. sfn42+sHd[view] [source] [discussion] 2026-01-17 20:48:32
>>accide+9md
Lol you guys are unbelievable. Go to Google, type in kwashiorkor, go to images and tell me that's indistinguishable from your average fatass.
replies(1): >>accide+SOe
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22. accide+SOe[view] [source] [discussion] 2026-01-18 09:26:51
>>sfn42+sHd
It's only a bit milder, because only one amino acid is missing, while google shows you extra severe cases, often mixed with general malnutrition.

There is evidence that methylmercurycysteine

1. occurs in sea life

2. occurs incorporated into proteins

https://doi.org/10.1039/B819957B

replies(1): >>sfn42+qvf
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23. sfn42+qvf[view] [source] [discussion] 2026-01-18 16:03:18
>>accide+SOe
Don't know what you're talking about, don't care. Bye.
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