Take alcohol. It is a drug, a poison, addictive, acute severe health problems are rare - although it can kill via the stupor it imposes but long term health and affects on productivity etc. Really bad.
So society may be better off without it. But then mind altering substances may be good even if they are bad for social cohesion and self medication. It is hard to be sober you have to take life as it actually is.
Make it illegal? Well that is almost orthogonal... why? What does it achieve to make it a moral outrage ... and who is the criminal? The brewer, the distributer or the drinker?
Then even if you decide that incarceration is a good think to do to people who do one of the 3 things - the prohibition shows that people will do it anyway. As a drug alcohol in particular is probably the easier to synthesize. You just need readily available pantry items and a jar. Other drugs need chenistry labs, precursor chemicals or plants. So that effects the affect of criminializing alcohol.
Then mix in its deep root in culture!
Now alcohols is discussed, what next... too much work...
That will have a different set of problems, solutions, unintended consequences of fixing the issue and so on.
So just treat gambling like its own thing. Even then casino poker vs. Slots vs. Lottery vs. Physical Bookie vs. Online booke vs. Crypto vs. Backstreet all have different subissues and may need to be legislated individually.