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1. Taikon+H5[view] [source] 2025-12-21 20:39:43
>>neom+(OP)
Interesting link: a company called Fractyl Health is studying a surgical procedure they call "Revita," that they hope can keep weight off for patients after they discontinue GLP-1s.[0]

The premise, IIUC, is that obesity is driven partly by mucosal overgrowth on the duodenum. This thicker-than-expected layer of mucus is less porous, which leads your digestive system to underestimate the number of calories you've consumed. Revita basically re-surfaces the duodenum.

So, the idea is that you get to a lower weight with the GLP-1 drugs, and then Revita can hopefully reset your set point there.

Their first clinical trial is still in progress, but I think it's interesting to watch.

[0]: https://www.fractyl.com/our-platforms/revita/

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2. hamand+l9[view] [source] 2025-12-21 21:05:18
>>Taikon+H5
> Revita basically re-surfaces the duodenum.

Does this reduce mucous production going forward? Otherwise, it seems like it would be a temporary effect.

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