I generally only run gaming graphics cards on dedicated gaming machines, not on workstations I need to be able to trust. You can't use accelerated graphics in qubes anyway, specifically because graphics cards are hard to trust.
My requirements from a workstation are:
1. MUST have 100% open source code loaded in system memory
2. SHOULD have open source software in the boot trust path (coreboot/tpm2 secure boot, etc)
3. SHOULD have open hardware to the furthest extent possible that meets my use case
4. SHOULD be fully auditable and tamper evident using at-home tools and methods (like the Precursor)