zlacker

[parent] [thread] 0 comments
1. gavinr+(OP)[view] [source] 2025-07-12 11:48:11
Tell me you never studied basic med chem or pharmacology without telling me...

You can't use animal models for dose, you have to convert to hED (Human-Equivalent Dosage). You can estimate this generally with allometric scaling:

https://drughunter.com/practical-pk-calculators

Also, animal physiology varies.

Beta-adrenergic agonists like clenbuterol make mice wildly muscular, which unfortunately is not the case in humans, for example.

[go to top]