I think it's the lack a of deeper meaning in the things we do have to do in this system. We're just cogs in a large machine that creates more and more wealth, but after you have enough to live a comfortable life that is no longer enough to make you care. There's no more purpose to it. Yet the pursuit of wealth is the only goal our economic system, and increasingly our culture as well, provides. Any other goal gets trampled under the herd of organizations seeking wealth for the purpose of making more wealth.