It is not just me and it is not just the smoking: https://www.cambridge.org/core/blog/2020/08/19/physically-he...
We have known for many years that people who suffer from schizophrenia die younger than expected, as much as 20 years younger than the general population. This appears unfair, and it was the inspiration of this work. Most people thought that this added risk of death was mostly due to the higher prevalence in schizophrenia of smoking, obesity and to other lifestyle differences.
For this reason, we recruited 40 patients with schizophrenia and an equal number of healthy controls, and scanned their hearts using a state-of-the-art approach, called cardiac magnetic resonance. This was performed at the state-of-the-art Robert Steiner MRI unit.
[...] Surprisingly, in our study we found that even after matching patients and healthy controls for age, sex, ethnicity and body mass index (BMI, deriving from height and weight); and after excluding any participants with any medical conditions, and other risk factors for heart disease, people with schizophrenia show hearts that are smaller and chunkier than controls. These changes are similar to those found in aging.