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1. Metace+(OP)[view] [source] 2023-08-03 16:19:21
Would the Ames test even make sense, given that bacteria don't have PCNA?
replies(1): >>flobos+Gz
2. flobos+Gz[view] [source] 2023-08-03 18:55:56
>>Metace+(OP)
The compound might have additional mutagenic mechanisms apart from the described PCNA interaction: it could cause direct chemical modifications to DNA, act as an intercalating agent that disrupts DNA replication and/or transcription, etc.
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