Devices and browsers will become locked down & attested blackboxes, manufactured by a handful of attested companies. Those companies will have trouble finding employees because less and less people will be interested in low-level stuff and security as there will be no devices and software to learn this stuff on. There will be less and less debugging options and "Software developer" will just be a dumb ape copy&pasting example corporate code, writing to the megacorp's support (based in india) if something won't work.