The usual Lisp do macro, for example. What a wretched bit of language design. Even now, whenever I encounter one, I have to stop and translate it in my head. Plus it can be very verbose. The reason do is so bad is that whoever designed it wanted to make it as functional (in the no-side effect sense) as possible. But sometimes side effects are just the right model.
BTW, there is a do in Arc. It's the new name for what used to be called progn. (It's surprising how much better that little change makes code look.)