zlacker

[parent] [thread] 1 comments
1. lucidr+(OP)[view] [source] 2022-07-28 16:15:56
To add to this, the deep learning field has already moved on towards MSA-less structure prediction. None of this would be possible without building on top of the work open sourced by Deepmind.

https://www.biorxiv.org/content/10.1101/2022.07.21.500999v1 https://www.biorxiv.org/content/10.1101/2022.07.20.500902v1

To be overly dismissive is to lack imagination.

replies(1): >>tomp+D31
2. tomp+D31[view] [source] 2022-07-28 21:43:48
>>lucidr+(OP)
How do we know these "MSA-less" models aren't cheating (i.e. learning all MSAs implicitly from their training data)? If they are, they would similarly fail on any "novel" AA sequence (i.e. one without known/learned MSAs)
[go to top]