If an outbreak were to happen in the United states just about everywhere would be near a CDC location: https://www.google.com/search?client=firefox-b-e&tbs=lf:1,lf...]
You've artificially limited the number of possible labs to those doing bioweapon research. If this isn't your claim there is no reason to do so and if there are more labs studying coronavirus it's far less coincidental.
But again, you really should read the article to understand what gain of function research is instead of insinuating I said COVID was a bioweapon.
Honestly, this is not a difficult distinction to understand. You have to wonder why people are so eager to conflate the two.
In any case, beyond gain-of-function, the WIV and Wuhan CDC also had the biggest program in the world to sample novel SARS-like coronaviruses from nature, from remote bat caves that no other humans had any reason to enter.
https://www.washingtonpost.com/world/asia_pacific/coronaviru...
If SARS-CoV-2 is a naturally-evolved virus accidentally released by scientists, then Wuhan is the obvious place for it to emerge. That could have been directly from a lab, or a researcher could have become infected on a sampling trip, traveled home from the sampling sites (~900 miles away, to be clear; Wuhan was not an expected natural spillover region), and seeded the infection there. None of this is anywhere close to proven, but the previous dismissal of any unnatural origin as a "conspiracy theory" was an outrageous, unscientific smear.
For a virus to originate in a city with one of three labs in the entire world conducting heavy-duty researching involving the exact kind of virus that unleashed this pandemic, with the stated intention of working with said viruses to make them more infectious (NOT for the purposes of making a bioweapon) that deserves special consideration. Especially with the fact that the animal the virus is thought to come from ranges 1500 miles south from said city, and started during a time that animal is typically hybernating.
How do I square that with this claim from the article?
> Eleven of its 23 coauthors worked for the Academy of Military Medical Sciences, the Chinese army’s medical research institute. Using the gene-editing technology known as CRISPR, the researchers had engineered mice with humanized lungs, then studied their susceptibility to SARS-CoV-2. As the NSC officials worked backward from the date of publication to establish a timeline for the study, it became clear that the mice had been engineered sometime in the summer of 2019, before the pandemic even started. The NSC officials were left wondering: Had the Chinese military been running viruses through humanized mouse models, to see which might be infectious to humans?"
What this describes seems like it could be circumstantial evidence of the PLA developing bioweapons. Certainly it isn't proof of anything, and as evidence it's not very strong. But I wouldn't call it 'zero.'
The WIV and Wuhan CDC sent grad students to hike through the wilderness to remote bat caves too far from any road or farm to have been exploited yet for any practical use. They chose those caves based on their expert predictions of where they expected to see the greatest diversity of novel coronaviruses.
There's obviously far fewer WIV grad students than guano harvesters; but the risk per person seems orders of magnitude higher, for an expert deliberately seeking a virus vs. a merely indifferent laborer. So that seems like a new and non-negligible risk to me, and thus one that requires investigation. Note that I'm not alone in this; Marc Lipsitch, for example, often mentions this possible pathway.
That's one of the independent vectors the author mentions that makes so many of us suspect very specifically a lab leak of a gain of function experiment: the virus started out very well adapted to humans.
https://www.pnas.org/content/102/23/8073
So if the Chinese military had in fact been doing this, I'd guess it was just basic research, in the same way that lots of American basic research links back to DARPA. Of course they fund it because they believe there might be a military application, but I see no reason to think that application would be bioweapons (vs. the same kind of beneficial applications described in the open literature).
Why is this relevant unless you're claiming that the virus that we've observed has been engineered in that way? Otherwise it seems like the chance of a coronavirus outbreak caused by poor handling in a lab is the same for any lab that's studying them for any purpose.
Most virologists say the way this virus works is unlike anything they’ve seen or expected so they can’t imagine how a human would have engineered it. Why do you think your feeling about the virus’s level of adaptation trumps the experts opinions?
> Of 23 samples that came from Wuhan, only three were type A, the rest were type B, a version two mutations from A. But in other parts of China, Forster says, initially A was the predominant strain. For instance, of nine genome samples in Guangdong, some 600 miles south of Wuhan, five were A types. [0]
[0] https://www.usnews.com/news/best-countries/articles/2020-05-...
It's a long article so I don't expect you to find the argument in it; it highlights the work of Alina Chan who compared a fast mutation rate of SARS-CoV as it better adapted itself to human to SARS-CoV-2. Here are titles of three of them I've saved but not read, May through September of last year:
SARS-CoV-2 is well adapted for humans. What does this mean for re-emergence?
Single source of pangolin CoVs with a near identical Spike RBD to SARS-CoV-2
COVID-19 CG: Tracking SARS-CoV-2 mutations by locations and dates of interest
They don't seem like obvious candidates to me, though. Both SARS v1 and SARS-CoV-2 show unpredictable, stochastic person-to-person spread, via super-spreader events. For a bioweapon that would ideally infect all the enemy but no one else, that's the last thing you want, hard to reliably get started and hard to reliably stop once it starts. So that reinforces my belief that if SARS-CoV-2 was of unnatural origin, it was almost certainly an accident during basic research.
This is literally not true.
Most virologists say the way this virus works is unlike anything they’ve seen or expected so they can’t imagine how a human would have engineered it. Why do you think your feeling about the virus’s level of adaptation trumps the experts opinions?
1) Citation on "most" please. The world is a big place, so you will be able to find a citation for any opinion. If you are going to say "most" then please back it up with a source.
2) gain-of-function research doesn't require a human to engineer a new virus. It is a way to essentially speed up evolution and allow nature to do the heavy lifting. You're arguing points that no on here is making.