"In 1990 she was offered a tenure track position at the University of Pennsylvania. Around this time, a different group of researchers developed a technique for injecting mice with RNA in such a way that those mice started to produce the proteins encoded by the RNA. [...] After six years of work at the University of Pennsylvania, due in part to a lack of interest from funding agencies in supporting her work, Karikó was demoted from her tenure track position. This type of demotion generally leads to the end of a scientific career. In the same year, she was treated for cancer and her husband encountered a visa problem, leaving him temporarily stuck in Hungary."
https://www.advancedsciencenews.com/pioneers-in-science-kata...
She was on the tenure track, and didn't get tenure.
That's denial of tenure.
Funding agencies provide funding based on grant reviews by... academics. So yeah, academics dismissed her novel ideas.