Perhaps not ones designed for carrying ballistic missiles.
Though this still isn't a perfect comparison because it ignores the fact that drone usage can be targeted to individuals, which is a factor that makes it more dangerous in our context of homeland operations.
> The government could in theory drive a ballistic missile launcher hidden in an 18-wheeler into any major US city - should we not allow trucks on the road?
This is a straw man, the Predator is a weapons platform, nothing is being hidden here.
From CBP's standpoint, it makes sense. What other unmanned aircraft could carry the same sensor package, while also being incapable of being armed? There's the Global Hawk, which costs about 10x more than a Reaper.
There's a reason that a civilian agency like NASA owns so many fighter jets (F-15/16s). R&D is expensive and there's no need to reinvent the wheel. (Also worth noting-- NASA also owns some Predator drones)
This is a model which is incapable of carrying armament.