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1. aetern+(OP)[view] [source] 2020-04-27 07:06:32
It would be great if they showed just one animation up front of the chaotic mess that actually represents reality. They could then show the simplified version so that we can actually see what is going on.
replies(1): >>regula+Cj
2. regula+Cj[view] [source] 2020-04-27 11:27:44
>>aetern+(OP)
https://www.researchgate.net/profile/Nicolas_Bellora/publica... is one example of the chaotic mess. What that shows is many RNA polymerase molecules walking up a gene. The horizontal line across the middle is DNA. The vertical tails hanging off it are RNA being built as the DNA is transcribed.

What that image drove home for me is:

1) that DNA transcription isn't something that happens rarely, or once-at-a-time. DNA is constantly being transcribed; proteins are constantly being built. The scale and rate isn't something I'd ever been taught.

2) How RNA polymerase works must be taking into account a hell of a lot of congestion. Polymerase molecules must constantly be bumping into each other.

3) How the picture would make no sense whatsoever unless you already know what the mechanism is.

I think it does make sense to start with the idealised process, as long as you follow up with messy reality.

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