zlacker

If I understand it correctly, ME has basically unrestricted access to RAM, bypassing the CPU and any restrictions the hypervisor and/or operating system may impose.

If I can peek and poke around in your RAM as I please, no amount of cleverness is going to save you if my intentions are malicious.

(Don't worry, though, I have no such intentions, and I don't fiddle with other people's RAM as a matter of principle, unless they ask me to. ;-))

>>krylon+(OP)
You can prevent certain things through address randomization and by using canaries to try and detect intrusions. I think if you made the system self modifying and incorporated a true RNG, it would be theoretically possible to obfuscate it at run time to malicious observers assuming attackers haven't seen observed the complete obfuscation process.