Every time I board a plane, I think what a crazy thing I am doing, but then I remember that I could be safe and snug in my house and still be in a plane crash.
To be fair, statistically, your living room is far more dangerous than the cabin of an airplane.
All things being equal, I would assume that you are safer in an environment that's stationary and reasonably sturdy, rather than in an aluminum tube at 40,000 ft above ground? Ok, as they say, all things are rarely equal, of course people are more likely to die of old age or of various diseases at home rather than while traveling (simply because old and terminally ill people probably don't travel that much), but I would say that skews the statistics against the living room and should be discounted. And at home you can engage in various activities that you probably won't do while on an airplane (electrical repairs, cooking...), but if you get hurt while doing that, that's also not a fault of the living room per se...