I have to admit, of the four, Karpathy and Sutskever were the two I was most impressed with. I hope he goes on to do something great.
When the next wave of new deep learning innovations sweeps the world, Microsoft eats whats left of them. They make lots of money, but don't have future unless they replace what they lost.
E.g. Oppenheimer’s team created the bomb, then following experts finetuned the subsequent weapon systems and payload designs. Etc.
So, if you want to meet with someone, instead of opening you calendar app and looking for an opening, you'd ask your AGI assistant to talk to their AGI assistant and set up a 1h meeting soon. Or, instead of going on Google to find plane tickets, you'd ask you AGI assistant to find the most reasonable tickets for a certain date range.
This would not require any special intelligence more advanced than a human's, but it does require a very general understanding of the human world that is miles beyond what LLMs can achieve today.
Going only slightly further with assumptions about how smart an AGI would be, it could revolutionize education, at any level, by acting as a true personalized tutor for a single student, or even for a small group of students. The single biggest problem in education is that it's impossible to scale the highest quality education - and an AGI with capabilities similar to a college professor would entirely solve that.
Do you work in education? Because I don't think many who do would agree with this take.
Where I live, the single biggest problem in education is that we can't scale staffing without increasing property taxes, and people don't want to pay higher property taxes. And no, AGI does not fix this problem, because you need staff to be physically present in schools to deal with children.
Even if we had an AGI that could do actual presentation of coursework and grading, you need a human being in there to make sure they behave and to meet the physical needs of the students. Humans aren't software to program around.
Sure, this doesn't mean you could just fire all teachers and dissolve all schools. You still need people to physically be there and interact with the children in various ways. But if you could separate the actual teaching from the child care part, and if you could design individualized courses for each child with something approaching the skill of the best teachers in the whole world, you would get an inconceivably better educational system for the entire population.
And I don't need to work in education for much of this. Like all others, I was intimately acquainted with the educational system (in my country) for 16 years of my life through direct experience, and much more since in increasingly less direct experience. I have very very good and very direct experience of the variance between teachers and the impact that has on how well students understand and interact with the material.
If you're looking for insight into the problems faced in education, speak to educators. I really doubt they would tell you that the quality of individual instructors is their biggest problem.