Every other theory requires involving many more unsupported hypotheses.
This would be obvious to the majority of the HN population in most cases, but the disinformation in this case is apparently quite effective.
What's the reason the lab is located in that city? Is there an underlying causal connection?
For example, is Wuhan prone to novel coronoviruses because of the local bat population, and so that was the logical place to site a coronavirus research lab?
If so, Occam's Razor would suggest that common connection as the more simple explanation.
Similarly, Sverdlovsk lab (the ground zero of 1979 anthrax outbreak) wasn't located there because Sverdlovsk specifically suspect to anthrax. An interesting tidbit, the party blamed the local farmer (wet) market for the outbreak there.