>>pentae+ei
Wire has E2E synced across devices and platforms, though its client and features lag behind Telegram (it's still better than Signal on features).
>>AnonC+Yl
Wire sends your social graph to the cloud.
Maybe this is an okay trade-off for you, but Signal's phone number as ID requirement means they can rely on the local contacts kept on your device and keep very little metadata about you on their servers.