I wish the Qubes OS the best of luck in future, and let's see how the GPU passthrough team goes.
The true pure faith requires compromises sometimes - when I need to run non-free software for work, I can keep it in a Qube VM and know it can’t mess anything else up. I trust Qubes to be reliable in a way I can’t ever remember experiencing with more traditional operating systems.
There’s a learning curve but I feel like I’m living (at least partially) in the promised land.