One of the most interesting OS project imo, I hope there will be some changes on the hardware side eventually but unfortunately I remain skeptical.
It would be nice if we could get an updated roadmap soon, perhaps after the Qubes OS team already gets some enterprise customers and things are more stable. The other one is already almost 2 years old (and behind).
I understand why (tying to avoid the "yet another Linux distro" stigma), but when you go to "What is Qubes OS?" in https://www.qubes-os.org/intro/ ; they fail to mention that is Linux based.
Well, to be fair this one has a FAQ entry: https://www.qubes-os.org/doc/user-faq/#is-qubes-just-another... ; although they try to understate that they use Linux.
If they want me to trust them, they're doing it wrong.
If you are already running an operating system on an Intel vPro (VT-d, TXT) laptop, you can likely run Qubes on that hardware.
If you are concerned about the Intel ME, you would need an Ivy Bridge vPro device like the Lenovo x230, plus skillz [0] that improves the security posture of all operating systems, including Qubes.