Giving LLM even read access to PII is a big "no" in my book.
On PII, if you need LLMs to work on production extracted data then https://github.com/microsoft/presidio is a pretty good tool to redact PII. Still needs a bit of an audit but as a first pass does a terrific job.
E.g. I used this method when I wanted to carry out a large (almost every source file) refactoring of Cytoscape.js. I fed the LLM a bunch of examples, and I told it to write a script to carry out the refactoring (largely using regex). I reviewed the script, ran the script, and then the code base was refactored.
At the time, agents were not capable enough of doing large-scale refactors directly, as far as I was aware. And the script was probably much faster, anyway.