How or why Scott Adams went completely of the rails is perhaps something we'll sadly never understand. Was this opinions he'd always had, but suppressed, did he somehow become radicalized or was it perhaps medically induced, e.g. a stroke or something. It was incredibly sad to see him throw away his life's work and go down a path most of us at least hadn't foreseen and die having alienated his fans.
It started at roughly the time of his divorce, so it's hard to imagine there's not a connection. But, of course, you're right that we'll never know.
I don't want to excuse his opinions but that's the sort of event that can change a person.
He did online chats, and did one immediately after. It's a tough watch. https://x.com/ScottAdamsSays/status/1046764270128484352
In fact, growing up in the very affluent part of my city, I saw a bunch of kids die using opiates to mentally escape the weird family fiefdoms where they [p/m]atriarch inexplicably wouldn't ever need for money, so went completely off the rails mentally. I was prescribed a bunch of opiates (including fent) after a bad ski accident, and can tell you that they basically work by turning down the volume on life around you. I can understand why someone would turn to them to mentally escape a bad family life.
About the only good thing I can say about recreational Xanax is that those kids are generally still alive in contrast to the ones who preferred opiates.