zlacker

>>PaulHo+(OP)
"The mechanism of action of ketamine primarily involves modulation of mitochondrial metabolism as opposed to NMDA receptor antagonism"

More evidence for Chris Palmer's 'Metabolic Theory of Mental Disorders'

>>MilkyW+Jl
It kinda makes sense if you consider depression to be a mechanism to get into winter hibernation. It's just we can't hibernate and even if we could, somebody has to pay them bills.

>>Murome+so
But are we built for hibernation? Or is the capacity for depression just a biological mistake for us?

>>port11+6t1
We are not build for anything. It's a legacy codebase. Some stuff stopped working, but nobody removed the surrounding utility codes and the config entry to enable it.

>>Murome+zj2
Damned legacy code and technical debt always ruining everything.