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[return to "Adenosine on the common path of rapid antidepressant action: The coffee paradox"]
1. k1musa+Vi[view] [source] 2025-12-06 00:26:03
>>PaulHo+(OP)
On chronic coffee consumption: "One meta-analysis found that RR coffee 0.757, RR caffeine 0.721 (12). Another one found RR 0.76, with an optimal protective effect at ∼400 mL/day (13). In comparison to many drug treatments that have an effect size in this range, this is not a small effect size. A risk reduction of 20 to 25% is quite impressive."

As if I needed another reason to drink coffee.

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2. boothb+Wj[view] [source] 2025-12-06 00:33:25
>>k1musa+Vi
One thing I've learned over the years is that specifically setting out to enjoy and appreciate something on a daily basis is beneficial to overall satisfaction with life. And for me, that's my morning cuppa before the rest of the house wakes up. Is it (just) the coffee or is it (also) the rituals surrounding coffee?
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3. ycombi+IJ[view] [source] 2025-12-06 05:07:18
>>boothb+Wj
Is it the addictive substance or the ritual I created around it?

I used to think this same thing, that my enjoyment of coffee was largely the ritual. But then I switched to decaf for quite a long time and all my little rituals fell away quite quickly.

I still occasionally drank coffee when I felt like the taste, but I certainly wasn’t performing daily morning ritual.

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4. erikro+ZR[view] [source] 2025-12-06 07:25:25
>>ycombi+IJ
I’ve switched to decaf full time and a my generalised anxiety basically went away. I love coffee and still drink it ritualistically. I probably drink more coffee now, at all hours of the day (caffeinated coffee after 12 really messed my sleep).

Also once per week I allow myself an espresso, and I get a nice buzz from it that lasts the entire day.

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5. ycombi+kX[view] [source] 2025-12-06 08:50:39
>>erikro+ZR
That’s cool. I’d like to quit again sometime but right now caffeine staves off migraines for me. And with a baby in the house I really don’t have the resources for that battle.
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6. erikro+1c2[view] [source] 2025-12-06 20:50:13
>>ycombi+kX
My gf has a migraine head and she’s tried going decaf but it just doesn’t work. Apparently caffeine does a lot to reduce the risk of migraines? So I’d probably just try to lower the dose until you find what works for you.
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7. ycombi+DW2[view] [source] 2025-12-07 05:30:28
>>erikro+1c2
I love the term “migraine head”. I’ve never seen that before. It’s gets across the idea that it’s just the way one’s head is quite nicely!
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