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[return to "Adenosine on the common path of rapid antidepressant action: The coffee paradox"]
1. k1musa+Vi[view] [source] 2025-12-06 00:26:03
>>PaulHo+(OP)
On chronic coffee consumption: "One meta-analysis found that RR coffee 0.757, RR caffeine 0.721 (12). Another one found RR 0.76, with an optimal protective effect at ∼400 mL/day (13). In comparison to many drug treatments that have an effect size in this range, this is not a small effect size. A risk reduction of 20 to 25% is quite impressive."

As if I needed another reason to drink coffee.

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2. boothb+Wj[view] [source] 2025-12-06 00:33:25
>>k1musa+Vi
One thing I've learned over the years is that specifically setting out to enjoy and appreciate something on a daily basis is beneficial to overall satisfaction with life. And for me, that's my morning cuppa before the rest of the house wakes up. Is it (just) the coffee or is it (also) the rituals surrounding coffee?
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3. reacto+al[view] [source] 2025-12-06 00:44:08
>>boothb+Wj
It’s 100% the addiction.

It’s ok, me too. At home I’m a 4-6 cup a day drinker. On the go 2-3 Starbucks. I have a serious problem.

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4. mrminc+Vl[view] [source] 2025-12-06 00:53:15
>>reacto+al
That was me too. Turns out I was just self-medicating for adhd. I still skip the meds on the weekend so I can enjoy larger quantities of coffee.
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5. Murome+Oo[view] [source] 2025-12-06 01:20:32
>>mrminc+Vl
I'm not gonna lie, double espresso with ritalin before work is pretty good too. It's the T+2 date which is uncool.
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6. nurett+FU[view] [source] 2025-12-06 08:15:47
>>Murome+Oo
Ritalin is a highly addictive substance that wrecks you, your life and the life of everyone around. Unfortunate that we have one in family.
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7. dotanc+8X[view] [source] 2025-12-06 08:46:46
>>nurett+FU
As a parent, tell me more. I have not yet heard this side of the coin.
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8. nurett+992[view] [source] 2025-12-06 20:21:16
>>dotanc+8X
Well, I'd say lots of words for how horrible and terrible it is to have Mr. Jekyll and Hyde around. Any specific questions?
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