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[return to "Adenosine on the common path of rapid antidepressant action: The coffee paradox"]
1. k1musa+Vi[view] [source] 2025-12-06 00:26:03
>>PaulHo+(OP)
On chronic coffee consumption: "One meta-analysis found that RR coffee 0.757, RR caffeine 0.721 (12). Another one found RR 0.76, with an optimal protective effect at ∼400 mL/day (13). In comparison to many drug treatments that have an effect size in this range, this is not a small effect size. A risk reduction of 20 to 25% is quite impressive."

As if I needed another reason to drink coffee.

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2. boothb+Wj[view] [source] 2025-12-06 00:33:25
>>k1musa+Vi
One thing I've learned over the years is that specifically setting out to enjoy and appreciate something on a daily basis is beneficial to overall satisfaction with life. And for me, that's my morning cuppa before the rest of the house wakes up. Is it (just) the coffee or is it (also) the rituals surrounding coffee?
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3. carlmr+bq1[view] [source] 2025-12-06 14:15:42
>>boothb+Wj
>enjoy and appreciate something on a daily basis is beneficial to overall satisfaction with life.

I'll couch this in a warning that you need to have the money for it, but for me an espresso machine and good grinder was such a great investment.

It's this thing I appreciate a lot every day.

If you're a drip coffee person I guess this won't apply and you can save a few thousand. Although I'd still recommend getting a grinder (not necessarily an expensive espresso worthy one) and good beans then.

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4. nobody+Br1[view] [source] 2025-12-06 14:28:12
>>carlmr+bq1
Drip coffee is amazing: A consistent grinder; fresh, light or medium roasted beans protected from oxidation; and a machine that heats the water to the correct brew temperature (190-195 F)is all you need.

The flavor profiles are akin to wines; no decanting required.

Extremely enjoyable in the early morning moments.

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5. port11+Gs1[view] [source] 2025-12-06 14:38:27
>>nobody+Br1
Espresso is my soft spot given my origins, but a good drip on paper filters (to remove some oils and cholesterol) is akin to good tea, full of aromatics. I disagree with the temperature, for me a blonde roast calls for 72 degrees Celsius (162F).
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6. nobody+wt1[view] [source] 2025-12-06 14:47:31
>>port11+Gs1
To be accurate, I should qualify that for me it’s “light/medium” and not a true blonde roast.

I haven’t had the pleasure of trying to brew my own blonde roast yet.

But I was amazed when I first tried a black coffee brewed properly, and it took me far longer than I want to admit to learn the basic nuances; it was a very fun journey though.

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