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[return to "Adenosine on the common path of rapid antidepressant action: The coffee paradox"]
1. k1musa+Vi[view] [source] 2025-12-06 00:26:03
>>PaulHo+(OP)
On chronic coffee consumption: "One meta-analysis found that RR coffee 0.757, RR caffeine 0.721 (12). Another one found RR 0.76, with an optimal protective effect at ∼400 mL/day (13). In comparison to many drug treatments that have an effect size in this range, this is not a small effect size. A risk reduction of 20 to 25% is quite impressive."

As if I needed another reason to drink coffee.

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2. boothb+Wj[view] [source] 2025-12-06 00:33:25
>>k1musa+Vi
One thing I've learned over the years is that specifically setting out to enjoy and appreciate something on a daily basis is beneficial to overall satisfaction with life. And for me, that's my morning cuppa before the rest of the house wakes up. Is it (just) the coffee or is it (also) the rituals surrounding coffee?
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3. reacto+al[view] [source] 2025-12-06 00:44:08
>>boothb+Wj
It’s 100% the addiction.

It’s ok, me too. At home I’m a 4-6 cup a day drinker. On the go 2-3 Starbucks. I have a serious problem.

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4. superk+Jy[view] [source] 2025-12-06 03:02:52
>>reacto+al
Caffeine is not chemically addictive. It can lead to depedency but that is not addiction. Motivation and wanting are not altered but unpleasant withdrawl effects can occur.
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5. Univer+jS[view] [source] 2025-12-06 07:30:33
>>superk+Jy
There is no real importance to the concept of “chemically addictive” and it has largely gone out of favor in psychology. Even physical behaviors like gambling and sex that obviously cannot directly, chemically act on reward system pathways, can still be just as life destroying addictive and challenging to quit as any drug. The dsm now classifies gambling disorder as an addiction.
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6. dist-e+mV[view] [source] 2025-12-06 08:23:08
>>Univer+jS
Caffeine, unlike some drugs and alcohol, doesn't cause severe withdrawal symptoms. Because of that, experts don't label regular caffeine use as an addiction.

https://www.webmd.com/diet/caffeine-myths-and-facts

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7. reacto+3p1[view] [source] 2025-12-06 14:05:04
>>dist-e+mV
There’s so many layers to this. First, there’s history: Coka-cola (originally made from a Kola nut and cocaine) was told they couldn’t put cocaine in their “medicine” anymore so they just sold it as a “soft-drink” without the cocaine.

Then there’s the beverage industry who pointed out there’s caffeine in tea leaves and other plant material and that it’s not a threat: (1) US vs 40 barrels and 20 kegs of Coka-cola. Ultimately reducing the amount of caffeine in soft-drinks.

Round and round we go allowing companies to use chemicals to keep us buying their consumables.

(1) https://en.wikipedia.org/wiki/United_States_v._Forty_Barrels...

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