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[return to "Adenosine on the common path of rapid antidepressant action: The coffee paradox"]
1. k1musa+Vi[view] [source] 2025-12-06 00:26:03
>>PaulHo+(OP)
On chronic coffee consumption: "One meta-analysis found that RR coffee 0.757, RR caffeine 0.721 (12). Another one found RR 0.76, with an optimal protective effect at ∼400 mL/day (13). In comparison to many drug treatments that have an effect size in this range, this is not a small effect size. A risk reduction of 20 to 25% is quite impressive."

As if I needed another reason to drink coffee.

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2. shevy-+4j1[view] [source] 2025-12-06 13:12:09
>>k1musa+Vi
> As if I needed another reason to drink coffee.

I tried it but coffee to me just tastes horribly bad. Chocolate on the other hand can be quite great (there is also a lot of horrible chocolate, but good chocolate has a better taste to me than coffee.)

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3. realo+Ek1[view] [source] 2025-12-06 13:25:48
>>shevy-+4j1
I like espresso-style coffee. Over the years i discovered that the very best espresso shots do have a rather strong chocolate note. No acidity, no bitterness.

Unfortunately I also found out that it is basically impossible to get that kind of quality from coffee shops. You must make it yourself, have the right equipment (the grinder is the most important one) and a lot of practice. Then you might have one in 10 god shots... but you taste it... you immediately recognize it.

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