zlacker

>>PaulHo+(OP)
On chronic coffee consumption: "One meta-analysis found that RR coffee 0.757, RR caffeine 0.721 (12). Another one found RR 0.76, with an optimal protective effect at ∼400 mL/day (13). In comparison to many drug treatments that have an effect size in this range, this is not a small effect size. A risk reduction of 20 to 25% is quite impressive."

As if I needed another reason to drink coffee.

>>k1musa+Vi
I don’t have hard data, but I think this optimal value is very closely approximated by coffee drinkers’ daily average. 400 ml is about 1.75 cups, and i think the normal distribution of coffee cups among drinkers is centered at ~2 cups. Makes me wonder if we’re all self medicating and accidentally finding the sweet spot.

>>pinkmu+Vz
Hmm to feel a bit elevated makes sense. I also have that with one glass of alcohol at certain times. Heart rate goes up, things get a bit more intense. It's a nice vibe if you're open to it. It's also a bit subtle.

For me what I've noticed: 2 cups hits the spot, but I always tend to drink more, around 4 cups. On the 3rd cup my mind gets jittery. It's not so much my body or anything and I don't experience the jitters strongly but at the same time I feel a stronger focus while noticing that stronger focus isn't getting anything extra done. Hence I call it mind jitters.

But I can imagine that at 2 cups people are genuinely just a bit elevated in certain ways.