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[return to "Adenosine on the common path of rapid antidepressant action: The coffee paradox"]
1. k1musa+Vi[view] [source] 2025-12-06 00:26:03
>>PaulHo+(OP)
On chronic coffee consumption: "One meta-analysis found that RR coffee 0.757, RR caffeine 0.721 (12). Another one found RR 0.76, with an optimal protective effect at ∼400 mL/day (13). In comparison to many drug treatments that have an effect size in this range, this is not a small effect size. A risk reduction of 20 to 25% is quite impressive."

As if I needed another reason to drink coffee.

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2. boothb+Wj[view] [source] 2025-12-06 00:33:25
>>k1musa+Vi
One thing I've learned over the years is that specifically setting out to enjoy and appreciate something on a daily basis is beneficial to overall satisfaction with life. And for me, that's my morning cuppa before the rest of the house wakes up. Is it (just) the coffee or is it (also) the rituals surrounding coffee?
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3. ycombi+IJ[view] [source] 2025-12-06 05:07:18
>>boothb+Wj
Is it the addictive substance or the ritual I created around it?

I used to think this same thing, that my enjoyment of coffee was largely the ritual. But then I switched to decaf for quite a long time and all my little rituals fell away quite quickly.

I still occasionally drank coffee when I felt like the taste, but I certainly wasn’t performing daily morning ritual.

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4. heavys+x61[view] [source] 2025-12-06 10:53:31
>>ycombi+IJ
It's both. In stronger drug addictions, the ritual itself is rewarding even if there are no drugs present in your system yet.

Add that to conditioned place preference and you have your rewarding coffee ritual.

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5. ycombi+v91[view] [source] 2025-12-06 11:27:49
>>heavys+x61
Yes, my morning coffee and cigarette breakfast was the most rewarding ritual. I basically couldn’t start my day without it!

Even though I quite smoking over 10 years ago I still remember it with the fondness of an old friend.

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