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[return to "Adenosine on the common path of rapid antidepressant action: The coffee paradox"]
1. k1musa+Vi[view] [source] 2025-12-06 00:26:03
>>PaulHo+(OP)
On chronic coffee consumption: "One meta-analysis found that RR coffee 0.757, RR caffeine 0.721 (12). Another one found RR 0.76, with an optimal protective effect at ∼400 mL/day (13). In comparison to many drug treatments that have an effect size in this range, this is not a small effect size. A risk reduction of 20 to 25% is quite impressive."

As if I needed another reason to drink coffee.

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2. boothb+Wj[view] [source] 2025-12-06 00:33:25
>>k1musa+Vi
One thing I've learned over the years is that specifically setting out to enjoy and appreciate something on a daily basis is beneficial to overall satisfaction with life. And for me, that's my morning cuppa before the rest of the house wakes up. Is it (just) the coffee or is it (also) the rituals surrounding coffee?
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3. paulet+BU[view] [source] 2025-12-06 08:15:04
>>boothb+Wj
Father of three here. I also enjoy very much this moment of the day, the calm before the storm. It was a real motivation to wake up a bit earlier.

One day, I decided to stop coffee for some weeks. My motivation to wake up before my kids vanished in a few days. I was quite surprised since it used to be a real pleasure. I guess the ritual part was much less important than the coffee chemical role.

I got back to coffe quite rapidly.

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