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[return to "Adenosine on the common path of rapid antidepressant action: The coffee paradox"]
1. k1musa+Vi[view] [source] 2025-12-06 00:26:03
>>PaulHo+(OP)
On chronic coffee consumption: "One meta-analysis found that RR coffee 0.757, RR caffeine 0.721 (12). Another one found RR 0.76, with an optimal protective effect at ∼400 mL/day (13). In comparison to many drug treatments that have an effect size in this range, this is not a small effect size. A risk reduction of 20 to 25% is quite impressive."

As if I needed another reason to drink coffee.

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2. boothb+Wj[view] [source] 2025-12-06 00:33:25
>>k1musa+Vi
One thing I've learned over the years is that specifically setting out to enjoy and appreciate something on a daily basis is beneficial to overall satisfaction with life. And for me, that's my morning cuppa before the rest of the house wakes up. Is it (just) the coffee or is it (also) the rituals surrounding coffee?
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3. reacto+al[view] [source] 2025-12-06 00:44:08
>>boothb+Wj
It’s 100% the addiction.

It’s ok, me too. At home I’m a 4-6 cup a day drinker. On the go 2-3 Starbucks. I have a serious problem.

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4. boothb+cn[view] [source] 2025-12-06 01:06:01
>>reacto+al
Well, that's a bit of an unfair projection; I'm fairly fastidious about keeping my consumption around 2-3 cups a day before 11am and taking occasional tolerance breaks without consequence. But if you feel like your coffee intake is a problem that you have trouble controlling, maybe cut back.
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