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[return to "The Thinking Game Film – Google DeepMind documentary"]
1. DrierC+R1[view] [source] 2025-11-30 16:18:09
>>ChrisA+(OP)
AlphaFold is optimization, not thinking. Propaganda 'r us.
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2. Rochus+xj[view] [source] 2025-11-30 18:16:06
>>DrierC+R1
Not sure why this is downvoted. The comment cuts to the core of the "Intelligence vs. Curve-Fitting" debate. From my humble perspective as a PhD in the molecular biology /biophysics field you are fundamentally correct: AlphaFold is optimization (curve-fitting), not thinking. But calling it "propaganda" might be a slight oversimplification of why that optimization is useful. If you ask AlphaFold to predict a protein that violates the laws of physics (e.g. a designed sequence with impossible steric clashes), it will sometimes still confidently predict a folded structure because it is optimizing for "looking like a protein", not for "obeying physics". The "Propaganda" label likely comes from DeepMind's marketing, which uses words like "Solved"; instead, DeepMind found a way to bypass the protein folding problem.
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3. tim333+nB[view] [source] 2025-11-30 20:28:02
>>Rochus+xj
I think if you watch the actual film you'd find they don't claim AlphaFold is thinking.
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