Reliable energy? Possible, but difficult -- need plenty of batteries
Cooling? Very difficult. Where does the heat transfer to?
Latency? Highly variable.
Equipment upgrades and maintenance? Impossible.
Radiation shielding? Not free.
Decommissioning? Potentially dangerous!
Orbital maintenance? Gotta install engines on your datacenter and keep them fueled.
There's no upside, it's only downsides as far as I can tell.
But what about when we’re making multi-year journeys to Mars and we need a relay network of “space data centers” talking to each other, caching content, etc?
We may as well get ahead of the problems we’ll face and solve them in a low-stakes environment now, rather than waiting to discover some novel failure scenario when we’re nearing Mars…