I have to admit, of the four, Karpathy and Sutskever were the two I was most impressed with. I hope he goes on to do something great.
When the next wave of new deep learning innovations sweeps the world, Microsoft eats whats left of them. They make lots of money, but don't have future unless they replace what they lost.
E.g. Oppenheimer’s team created the bomb, then following experts finetuned the subsequent weapon systems and payload designs. Etc.
Engineering Level:
Solve CO2 Levels
End sickness/death
Enhance cognition by integrating with willing minds.
Safe and efficient interplanetary travel.
Harness vastly higher levels of energy (solar, nuclear) for global benefit.
Science: Uncover deeper insights into the laws of nature.
Explore fundamental mysteries like the simulation hypothesis, Riemann hypothesis, multiverse theory, and the existence of white holes.
Effective SETI
Misc: End of violent conflicts
Fair yet liberal resource allocation (if still needed), "from scarcity to abundance"People want their suburban lifestyle with their red meat and their pick-up truck or SUV. They drive fuel inefficient vehicles long-distances to urban work environments and they seem to have very limited interest in changing that. People who like detached homes aren't suddenly affording the rare instances of that closer to their work. We burn lots of oil because we drive fuel inefficient vehicles long distances. This is a problem of changing human preferences which you just aren't going to solve with an AGI.
With abundant electric cars (at this future point in time) and clean electricity powering heating, transportation, and manufacturing, some AIs could be repurposed for CO2 capture.
It sounds deceptively easy, but from an engineering standpoint, it likely holds up. With free energy and AGI handling labor and thinking, we can achieve what a civilization could do and more (cause no individual incentives come into play).
However, human factors could be a problem: protests (luddites), wireheading, misuse of AI, and AI-induced catastrophes (alignment).