These are huge losses. Pachocki led pre-training for GPT-4, and probably GPT-5. Brockman is the major engineer responsible for the efficiency improvements that enabled ChatGPT and GPT-4 to be even remotely cost-effective. That is a piece that is often overlooked, but OpenAI's advantage over the competition in compute efficiency is probably even larger than the model itself.
https://time.com/collection/time100-ai/6309033/greg-brockman...
But yeah, since Sam and Greg were apparently pushed out because they were building too good of a business any OpenAI employees that were aligned with them are likely to jump ship and join them, and OpenAI will revert to the non-profit research lab it started out as.