We keep encountering situations like this where a new chemical compound was introduced, becomes ubiquitous in our diets or environments and only later do we find out "Oops, it has serious health or environmental consequences."
It is worth the cost of slower introduction of new materials to take the time to ensure that those materials are safe. We're still paying the cost of introducing lead into our environment in a myriad of subtle ways. We still don't fully understand what the cost of the introduction of microplastics or PFAS is going to be. And regardless of the whether this particular study holds up under replication it is looking increasingly likely that aspartame is not something we should be consuming.
And what's most frustrating is that the people who profited most from these compounds never pay for the damage they cause to generations.
The people were naive. It's not like they had malicious intent. 'Don't hate lazy people - they did nothing'
See also the Cuyahoga catching on fire. Water burning is quite a poster child.
It is worth noting that this probably had more to do with the awful state of the city sewage system, so the water was well known to be contaminated. Luckily we've improved somewhat with sewage (I think).
Although anecdotally I've had a local lake closed for weeks at least due to toxic red algae blooms related to run off from farms (I believe it's fertilizer runoff that's attributed to these blooms)