zlacker

>>giulio+(OP)
The headline is misleading. The actual study proved that the recorded date of admission to hospital in Ireland with ST-segment elevation myocardial infarction was increased on a Sunday and Monday. Increased admissions on a Monday is not that unusual given that people often seek medical attention after the weekend but maybe more surprising is the increase on a Sunday. https://heart.bmj.com/content/109/Suppl_3/A78

>>barbeg+ue
From the methods section of the abstract: “We excluded post-fibrinolysis patients, patients with old stents, and those who presented more than 24 hours after the onset of pain.”[edit: I misread the PDF version which included multiple abstracts, the methods I’m referring to was from a separate study with the title cutoff, this specific abstract didn’t specify. But from below and table 1 in: https://jamanetwork.com/journals/jama/article-abstract/20140... which looked at 68,000 STEMIs, 3.1% presented > 12 hours and 8.4% had an unknown time of symptom onset. Wouldn’t explain the magnitude of effect seen in this study. Circadian effects on STEMI and increased incidence on Monday are not new observations.]

Don’t think late presentation STEMIs are that common to begin with for your argument to have logical sense, this is the worst form of a “heart attack”.

From this single center study presentations > 12 hours only comprised 10%.

https://www.ingentaconnect.com/content/wk/jcarm/2017/0000001...

>>halduj+7g
Thanks for links to those extra studies. The 3.1% and 10% presented > 12 hours are averaged across all days of the week not just the Sunday to Monday gap which is likely to be greater given the reduction in public services in Ireland on a Sunday. Do you know of previous studies which report Monday as being particularly risky? I can only find references to time of day (circadian cycle) which obviously make sense given how many bodily processes are linked to a circadian cycle but I'm skeptical about a weekly cycle (which I find confusing to be referred to as circadian also)