zlacker

>>MindGo+(OP)
Obtaining this dataset prior to alphafold would have cost on the order of $200 trillion. https://twitter.com/wintonARK/status/1552653527670857729

Anyone knowledgeable know if this estimate is accurate? Insane if true

>>alphab+to
It doesn't make any sense on multiple levels. This is a computational prediction and there was no computational alternative- for many of these proteins would never have had a structure solved even if you spent the money. They are just taking $cost_per_structure_solved * number_of_remaining_structures and assuming that things scale linearly like that.

Note that crystallographers are now using these predicftions to bootstrap models of proteins they've struggled to work with, which indicates the level of trust in the structural community for these predictions is pretty high.