HOWEVER, I like that Qubes has Debian. I'm used to it, it's predictable, etc etc. Some of my work basically even depends on it. With Spectrum I'd have to be stuck with the quirks of Nix, which I understand are less friendly than Debian. If I have the option of falling back to the equivalent of a Debian template, I'd likely switch.
You can use Salt to automate this work: https://www.qubes-os.org/doc/salt/.
Qubes I think could benefit from more resources for ramp-up documentation.