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[return to "Ask HN: What scientific phenomenon do you wish someone would explain better?"]
1. vmcept+Yu[view] [source] 2020-04-26 23:17:02
>>qqqqqu+(OP)
Has someone that thought they were taking LSD ever turned into a permanent schizophrenic zombie or in a mental institution, or is it all urban legend. If someone that didn't know they were predisposed to mental illness, is it applicable to dismiss their experience in order to maintain how safe LSD is?

If any of this is true, are there any sources aside from "my friend's friend's brother took too much and now he is....", and what is the scientific explanation and do we know enough about the mind at all?

I feel like LSD has a lot of contradictory information out there, and the proponents feel the need to hand waive concerns away because it is 'completely harmless and leaves your system in 10 hours'. But when nobody knows what they're actually getting because it doesn't exist in a legal framework, then it muddies the whole experience.

People say certain doses can't do more effect than lower doses after a certain threshold. It seems like the same people say "omg man 1000ug you are going to fry your brain!"

What is the truth? If it "just" had an FDA warning like "people with a family history of schizophrenia should not take it", that would be wildly better than what we have today.

Please no explanation about shrooms. Just LSD the 'research chems' distributed as LSD.

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2. knzhou+OA[view] [source] 2020-04-27 00:09:34
>>vmcept+Yu
This entertaining article lists what happened to the early LSD researchers: https://slatestarcodex.com/2016/04/28/why-were-early-psyched...
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3. vmcept+nG[view] [source] 2020-04-27 01:02:29
>>knzhou+OA
entertaining, the comments are a good addendum but are just as speculative. maybe there just isn't good information, its just more of the contradictory information.

"lasting permanent changes, obviously"

"I’ve personally seen several people experience total amnesia after tripping on high doses." No further information.

"Not lasting permanent changes"

what.

Names, sources, medical records, news reports, court cases, there has got to be something out there!

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