(downvotes incoming in 3...2...1....)
Edit: it is also right on top of the article - "her long-awaited sequel to The Handmaid’s Tale, was released, and she became something else entirely: a worldwide cultural phenomenon. The novel, set in a not-so-distant United States where fundamentalist fascists have gained power and stripped away women’s rights"
(Although I was referring to her comments before the release of the new book, but the new book confirms it).
There were demonstrations inspired by her fiction. In the real world. She commented on those.
Since then she has released a whole book about the US becoming a handmaid's tale world. That book is fiction. Here Twitter comments before that were not. They refer to the real world.